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The author notes that in drilling cavities, the sharper the bur, the less obtundent needed. The author also addresses other drugs (hemostatic, anticoagulants) and those acting on the cardiovascular system or on the blood vessels.

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Clinical pharmacology is the science of drug use in humans. Clinicians of all specialties pre A Textbook of Clini Goodman and Gilman's The Pharmacological.

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Thus, pharmacology is the science of the drugs system. It includes the knowledge of history, source, biochemical and physiological effect, mechanism of action.